Full record for mutation n.

Definition an organism which has arisen by genetic mutation; a mutant
OED requirements antedating 1931
Earliest cite Edmond Hamilton
Comment OED update June 2003: SF sense added with earliest cite of 1941 (Heinlein).
Last modified 6 July, 2008

Citations for mutation n.

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1931 E. Hamilton Man Who Evolved in I. Asimov Before Golden Age (1974) 37 There would be super-men, bodiless heads, pure brains; only to be changed by the last mutation of all into the protoplasm from which first it had sprung!
1931 E. Hamilton Man Who Evolved in I. Asimov Before Golden Age (1974) 27 He will be changed millions of times faster than ordinarily, will go forward in hours or minutes through the evolutionary mutations that all mankind will go forward through in eons to come!
1931 E. Hamilton Man Who Evolved in I. Asimov Before Golden Age (1974) 26 For it is the cosmic rays, beating upon every living organism on earth, that cause the profound changes in the structure of those organisms which we call mutations.
1931 E. Hamilton Man Who Evolved in I. Asimov Before Golden Age (1974) 34 I have gone this far along the road of man's future evolution, and am going on to the end of that road, am going to attain the development that the last mutation possible will give me!
1946 Astounding Sci. Fiction Dec. 144/1 It would be impossible for a despised mutation ever to become Lord Leader.
1946 Astounding Sci. Fiction Dec. 144/1 It would be impossible for a despised mutation ever to become Lord Leader.
1950 R. Heinlein Farmer in Sky (1975) ix. 100 He said that ‘M-G’ meant ‘mutation-Ganymede’ and the other meant ‘normal terrestrial.’
1968 C. Wilber & G.L. Coon Space Seed in J. Blish Star Trek 2 (1968) 113 The sports and monsters‥almost surely were spontaneous mutations erupting from all the ambient radioactivity.
1972 J. Blish Star Trek 5 41 Unaccountable rarities do occur. A mutation?
1983 S. Marshak & M. Culbreath Triangle iv. 29 This is the age of the mutation of Oneness.
1989 O. Butler Imago (1991) ii. v. 112 It was too hot to eat, but I brushed it off and broke it open. It was well cooked, steaming hot, spicy, and sweet. It had not existed before the Humans had their war. Lilith said it was one of the few good-tasting mutations she had eaten.
1997 J. Sherman & S. Shwartz Vulcan's Forge i. 3 Rabin winced at the thought of the resulting abnormally high rates of cancer and lethal mutations.
1998 L. A. Graf & M. J. Friedman War Dragons x. 143 Or a recent mutation, or even a result of genetic engineering.